Black Pepper has also been found to increase the serum levels

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Important Note:: Based upon the literature research and the personal experience. This information is for educational purposes and is not considered complete or guaranteed to be accurate. Pure essential oils are powerful compounds, care must be taken in use. The information provided is not intended as a substitute for consulting with your physician or other health care provider. The Institute of Complementary Therapies, LLC is not responsible for any adverse effects or consequences resulting from the use of any of the suggestions, preparations, or procedures discussed on this web site.
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In a double-blind crossover study, 5 mg of piperine daily for 14-day periods resulted in significant increases in serum beta-carotene levels. The same dose of piperine produced similar results in another study, this one involving coenzyme Q10.
The claim that piperine may aid in the digestion of food is based on some experimental animal data showing that dietary piperine seems to enhance pancreatic amylase lipase, trypsin and chymotrypsin activity.
The claim that piperine may have some anticonvulsant activity comes, in part, from China, where the substance is used in an effort to treat some forms of epilepsy. In mice, piperine injected intraperitoneally inhibited clonic convulsions induced by kainate. It did not significantly block seizure activity induced by L-glutamate, N-methyl-D-aspartate or guanidinosuccinate.
The mechanism of piperine's putative anti-inflammatory activity may be accounted for, in part, by piperine's possible antioxidant activity. There are a few studies suggesting that piperine may inhibit lipid peroxidation. Piperine has been shown to stimulate the secretion of the digestive enzymes pancreatic amylase, trypsin, chymotrypsin and lipase in rats. However, piperine appears to have this activity when administered with other spice bioactives, such as capsaicin and curcumin, and not when administered by itself.
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